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It is injected daily rather than weekly, has a shorter half-life (approximately 13 hours versus 7 days for semaglutide), and produces somewhat less weight loss
Does glucagon receptor activation increase hypoglycemia risk
JANUMET is contraindicated in patients with an estimated glomerular filtration rate (eGFR) below 30 mL/min/1.73 m2 [see Contraindications (4) and Warnings and Precautions (5.1)]
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Routine follow-up appointmentstypically scheduled at 2-4 week intervals during the first three monthsallow your prescriber to assess symptom trends and make proactive adjustments before gastroparesis becomes limiting
While the science is still emerging, ongoing studies funded by the National Institute on Drug Abuse suggest significant potential across alcohol, stimulant, and compulsive behavior disorders
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