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Additionally, the two exemplified implementations each have only three hydrogen bond donors (NH), and the large ring conformation exhibits flexibility, which can enhance gastrointestinal absorption of the drug to meet the bioavailability requirements for oral medications

The C-terminal amide blocks carboxypeptidase cleavage

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As the previous study failed to define known thyroid hormone response elements (TREs) for Cyp8b1 22 , whether it is transcriptionally by TR has been a longstanding mystery

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