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A recent poll found that 18% of adults reported taking a GLP-1 RA in their lifetime, an increase from the previous years poll, which cited 12% of Americans reported GLP-1 RA use in their lifetime (5, 6)
When gastric acid becomes too prevalent, the stomach lining can become susceptible to irritation
2017 Cell study, with subsequent independent confirmations in human chondrocytes (Huang 2021), mouse Leydig cells (Zhang 2020
"Nearly all the evidence is retrospective, drawn from insurance claims and electronic health records separating the drug from the condition it treats is the hard part, and no study has managed it cleanly." He said it was important people did not stop taking their medication on the basis of this safety update
References: Wilding JPH, et al
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