Tier 2 (Moderate risk): 3x to 5x the prescribed dose, or any dose in a patient with a cardiovascular or hepatic comorbidity
B12 shots and NAD+ injections
Being a vegetarian or vegan : This group consumes less foods that are naturally high in vitamin B12, such as beef and poultry (and sometimes dairy and fish too), which means their intake of vitamin B12 is lower whether their absorption is adequate or not
Pros of Injections Bypasses the Digestive System: Because the vitamin is injected directly into the bloodstream, it bypasses any absorption issues in the stomach or intestines
Current Research and Future Trends Expanding Clinical Applications Ongoing studies are exploring the role of AOD-9604 in treating metabolic conditions such as: Type 2 diabetes Insulin resistance Non-alcoholic fatty liver disease (NAFLD) Up to 95% of individuals with type 2 diabetes also present with NAFLD, emphasizing the need for multi-functional metabolic therapies Joint Health & Cartilage Regeneration In addition to fat metabolism, AOD-9604 may stimulate cartilage repair and support joint health
NNMT (Nicotinamide N-Methyltransferase) Inhibition Potently and selectively binds to the nicotinamide binding site of NNMT, blocking the methylation of nicotinamide using SAM 4