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The lack of extensive safety studies means that potential rare or delayed adverse effects have not been fully characterized

They are not intended for human or animal consumption

[7] They are generally well-tolerated, with common adverse effects including headache, facial flushing, nasal congestion, and dyspepsia

Our findings demonstrated that the mouse intestinal pH was neutral to weakly alkaline from the duodenum to the rectum, and the amount of hydrogen contained in the large intestine was increased by administration of the Si-based agent (Fig

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