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As we age, fat accumulation, especially visceral fat, contributes to a host of age-related issues, including inflammation and reduced energy levels
In addition, FGF21 has been reported to protect the heart from inflammation and fibrosis caused by high-fat diet-induced cardiac steatosis (154)
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5 Amino 1 MQ: Your New Go-To Peptide
Its defining structural feature is the gamma-glutamyl linkage: the glutamate residue is joined through its side-chain carboxyl rather than the usual alpha-peptide bond, which makes the molecule resistant to most intracellular peptidases and means it is cleaved almost exclusively by gamma-glutamyl transpeptidase at the outer cell surface (Zhang, Forman and Choi, Methods in Enzymology, 2005)
