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Acknowledgments We would like to thank all the participants and co-workers in Royan Institute for their assistance in this study

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People with liver or kidney disease , or a history of organ dysfunction

New or worsening fatigue that does not improve with rest

The BP protein called hydrolysate (enzymatically cleaved BP protein) can have strong anticancer activity by inhibiting human bronchogenic carcinoma (ChaGo-K1 cells), resulting in IC 50 value of 1.37 g/mL (174, 176)

The scondary goal of the study was to compare the effects of combined treatment of cagrilintide and semaglutide versus treatment with cagrilintide alone and how the effected HbA1c levels and various parameters of glycemic control and bodyweight as well as the safety and tolerability of the treatment