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Notably, oral semaglutide (Wegovy) became the first oral GLP-1 approved for weight loss and weight loss plus secondary CV risk reduction

Glucagon receptor activation increases resting energy expenditure through multiple mechanisms, including enhanced hepatic metabolic activity, increased thermogenesis, and elevated fat oxidation rates

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To predict the risk of lower limb amputation in diabetic foot ulcer patients by using the DIAFORA score (Diabetic Foot Risk Assessment Score)

Musso G, Gambino R, Cassader M (2010) Obesity, diabetes, and gut microbiota: the hygiene hypothesis expanded