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9 Future directions and challenges TBI has emerged as a significant global health and socioeconomic challenge, placing a substantial healthcare burden on contemporary society and necessitating the development of efficient treatment strategies (Maxwell, 2012)

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Masini, A., Ceccarelli, D., Trenti, T., Gallesi, D

Markets (2020): ~807 in trials

This escalation pattern is consistent with other GLP-1 receptor agonists and should be considered when designing preclinical study protocols that aim to replicate clinical pharmacokinetics

Originally developed and approved by the FDA in 2017 as a treatment for type 2 diabetes, Ozempic has shown promising results in helping individuals lose weight