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The prevalence of the disease in childhood and adolescence ranges between 0.5% and 2%
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Participants using a GLP-1 RA had a greater reduction in HbA 1c 5.4 mmol/mol (0.5%) vs 2.6 mmol/mol (0.2%) and serum cholesterol (0.4 mmol/l vs 0.1 mmol/l) than those in the SGLT2i cohort
The pattern makes biological sense
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Administration of resveratrol (20 mg/kg body weight) to adult rats significantly increases the number of proliferating and newly generated cells in the hippocampus, with upregulation of p-CREB and SIRT1 proteins (Kumar et al., 2016)
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