Furthermore, a network meta-analysis examining the effects of GLP-1 RA therapy on body composition reported a greater reduction in lean body mass in the intervention group compared with placebo or active comparators (mean difference = 0.86 kg, 95%CI: 1.30, 0.42)
In studies on cardiovascular diseases, GLP-1RAs have shown potential benefits
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PMCID:PMC11228148
Common semaglutide side effects include nausea, vomiting, diarrhea, and constipation, which typically resolve within a few weeks as your body adjusts