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Hormonal changes can intensify things further

Taspoglutide, a novel human once-weekly GLP-1 analogue, protects pancreatic -cells in vitro and preserves islet structure and function in the Zucker diabetic fatty rat in vivo

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Thus, the development of depression will not only seriously impair the quality of life of GD patients but also aggravate the original condition of GD and affect its prognosis

Both of these things, along with increased physical activity, help to lower body weight and lead to weight reduction