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Others may move in the opposite direction

Effects of exenatide combined with lifestyle modification in patients with type 2 diabetes

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While longer-term interventional work is necessary to understand how RT directly influences directional sensitivity of the cerebral pressure-flow relationship, the findings from Korad et al and Roy et al do indeed suggest that frequent exposure to oscillatory pressure challenges via resistance exercise may habituate the arteries to better handle both elevations and drops in mean arterial pressure and avoid hyperperfusion and pre-syncopal and syncopal responses, respectively (Korad et al., 2024

GLP-1RAs are a relatively new class of injectables that are effective at reducing HbA 1c , have a low risk of hypoglycaemia when given as monotherapy or in the absence of sulphonylureas (SU) or insulin, and have the potential for weight losskey considerations when treating a typical obese patient with T2DM [4]

The therapy may also increase muscle mass, reduce body fat, and enhance exercise performance, supporting an active lifestyle