[PMID: 6722145] PubMed record related to this compound for laboratory literature review
In summary, in the Si-DSS group, the colon was thought to be protected from oxidative stress by detoxification of LPO via enhancement of the glutathione/GPx system
Patients with severe gastrointestinal disease , including gastroparesis, may not tolerate these medicines well due to their effect on gastric emptying
Indeed, AA and ferric maltol (approved for the treatment of iron-deficiency anemia in IBD 31 ) triggered epithelial LPO, Cxcl1 expression and small intestinal neutrophilic infiltration in Gpx4 +/IEC mice
If validated, GLP-1RAs could shift the landscape of diabetes management with an added advantage in cancer prevention
Peer review Peer review information Nature thanks Lucas Sullivan and the other, anonymous, reviewer(s) for their contribution to the peer review of this work