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Second, its relatively small size and amphiphilic character allow partial blood-brain barrier transit, but enzymatic degradation in plasma competes with CNS entry at every moment after injection
A., Curran, T
Currently Available GLP-1 RAs Currently available GLP-1 RAs are summarized in TABLE 1
Weekly dosing patients can continue taking these injections once per week but at a lower dose
This provides a middle ground between purely systemic and directly local administration
Some studies have shown a reduction in major adverse cardiovascular events by 18-20%
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