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Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3- methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl] thiazolidine): A highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes

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( d ) Brain-wide Fos expression over area across three groups of mice: WT:Gnas fl/fl [saline] (n = 4 mice), WT:Gnas fl/fl [sema] (n = 7 mice), Glp1r-ires-cre:Gnas fl/fl [sema] (n = 5 mice)

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The review process typically happens within 24 to 48 hours, though some members report faster turnaround