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Studies have proven that newly synthesized nanomaterial selenoprotein nanoparticles (Se@BSANPs) can reduce the activity of caspase-1 and the proinflammatory factor IL-1 by upregulating the level of GPx-1 and inhibiting the activation of NLRP3 inflammatory bodies in renal tubular epithelial cells after IRI and IL-18

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The pilot screen revealed some host genes that increased or decreased Cryptosporidium growth when knocked out (Fig S1H), from which we selected RhoA and Rab8a as our controls, as disabling these genes decreased and increased parasite growth respectively