In Phase 2 trials, treatment with survodutide led to greater reductions in both HbA1c levels and body weight compared to placebo after 16 weeks
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This could be due to longer half-life (of 26 h) of GFP protein, due to which the small decline in its expression was beyond detection
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The strongest outcomes in clinical trials and in real-world settings consistently involve a GLP-1 protocol combined with a reduced calorie diet, regular exercise, strength training, and ongoing physician oversight
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