Ozempic, also called semaglutide, may be the most well-known, but five other GLP-1s in an injectable form are used to treat diabetes
Semaglutide is a once-weekly injection that supports weight loss and helps regulate blood sugar
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Clinical trials demonstrate that GLP-1 drugs reduce liver fat content, improve liver enzymes, and in some cases achieve resolution of nonalcoholic steatohepatitis (NASH)
It incorporates a functional maleimido group at the C-terminus that allows it to covalently bind plasma proteins such as serum albumin
The Science Behind GLP-1 and Hormone Interaction GLP-1s mimic the action of the naturally occurring GLP-1 by activating the GLP-1 receptor and consistently impacting blood sugar, insulin, and appetite regulation