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Additionally, NAD + is also needed to support fatty acid oxidation
doi: 10.1016/j.eururo.2021.01.014 40 Mateo-OteroYLlavaneraMTorres-GarridoMYesteM
In addition, the tricarboxylic acid cycle serves as a redox platform for integrating metabolic signals from glycolysis and amino acid catabolism to produce PUFAs, which also induce ferroptosis
Current NICE guidance (NG49) emphasises lifestyle modification as the primary treatment for NAFLD, including weight loss, dietary changes, and increased physical activity
Present at millimolar concentrations in most mammalian cells, GSH is involved in virtually every aspect of cellular defence and metabolic regulation
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