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Possible downsides include nausea, constipation, fatigue, and appetite rebound if stopped too quickly

doi:10.1016/j.beem.2018.06.007 Wilding JPH, Batterham RL, Calanna S, et al

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Analysis of blood parameters confirmed improvements in key markers of glucose and lipid metabolism, such as blood lipid levels, cholesterol, liver damage markers, and HOMA-IR

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