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Retatrutide is administered as a once-weekly subcutaneous injection of up to 12 mg

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Two further cautions: Coskun 2018 measured tirzepatide GIPR EC50 at 0.0224 nM in a standard-density system, 45 more potent than Willards low-density figure, which is why standard-density values cannot be mixed into this comparison

doi: 10.1007/s13577-020-00461-4 243 ChenJLuoXLiuMPengLZhaoZHeCet al