This compound regulates the oxidative burst that is required for optimal immune cell activation (244, 245)
Symptoms of vitamin B12 deficiency may include any or all of the following: Chronic fatigue (4) or low energy (despite getting enough sleep) Shortness of Breath Macrocytic anemia (5) High MCV (mean corpuscular volume on CBC analysis) Neurological changes that can mimic dementia (6) Depression (7), anxiety, and other mood disorders Difficulty with concentration (8) Brain fog Skin changes like hyperpigmentation (9), vitiligo, or angular stomatitis Hair changes (including hair loss (10)) Perhaps you can relate to one or more of these symptoms noted above
PMCID: PMC9794587
It can also manifest as a general flushing of the face and neck or small, pinpoint red spots that may feel sensitive or warm to the touch
Natural sources include animal products like meat, fish, eggs, and dairy
Once aggregation begins, it is autocatalytic soluble peptide is consumed by the growing aggregate