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This evidence suggests that despite their success in achieving initial weight loss, these drugs alone may not be sufficient for long term weight control, say the researchers
Dosages can be adjusted based on training cycles, body composition goals, and recovery demands
Reproducibility Crisis: This is a real concern in science today
After the run-in period, those with inadequate glycemic control (A1C 6.5% to 10%) were randomized 1:1 to the addition of sitagliptin 100 mg once daily or glipizide for 52 weeks
Experts say there are plausible albeit unconfirmed explanations, noting for example that GLP-1 medications may interfere with the efficacy of oral contraceptives or increase fertility in women because they help with weight loss
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