Discontinuation rates due to gastrointestinal adverse effects ranged from 4% to 7% across clinical trials
Still, the research cited post-usage boomerangs and found that 50% of previous users are likely to use these drugs again
Injected semaglutide and tirzepatide have the strongest trial data supporting efficacy
Gabe MBN, Skov-Jeppesen K, Gasbjerg LS, et al
However, high dose vitamin E supplements those which provide more than 300 mg per day can interact with the blood thinners aspirin and warfarin ( They can also interfere with tamoxifen, a drug used to treat breast cancer, and cyclosporine, an immunosuppressant used by people who have received an organ transplant ( If you have any concerns about potential interactions between vitamin E supplements and your medications, you should consult your healthcare provider
However, the GLP-1 craze is fairly unique