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Systemic toxicity-collectively termed local anesthetic systemic toxicity (LAST)-necessitates prompt airway control, seizure suppression with benzodiazepines, and lipid emulsion therapy, which sequesters lipophilic drug molecules and improves hemodynamic stability
Walker MA et al
More studies are necessary to determine what factors may underlie the link
Long-term safety and effects of tesamorelin in HIV patients with abdominal fat accumulation
Factor Xa and prothrombinase complexes bind to PS on MPs and RBC surfaces, amplifying thrombin production and accelerating coagulation
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