UMMC 2014)
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n=179 ALC, n=174 control), the pooled estimate was similarly in the direction favoring ALC (SMD 0.81, 95% CI 2.42 to 0.81
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Semaglutide weight loss mechanism #1: it prevents blood sugar spikes Well-functioning L-cells located in the gut produce natural GLP-1 after food intake, which inhibits potentially damaging postprandial glucose excursions (PPGEs) in laymens terms, post-meal blood sugar spikes (PPG inhibition is why, before the FDA approved GLP-1 analog semaglutide for weight loss therapy, it was commonly used in the treatment of diabetes.) This blood sugar-limiting effect mediated by a complex interplay of hormones is called glucose homeostasis. Semaglutide, a GLP-1 analog, does the same thing to regulate glucose homeostasis, but with greater efficacy due to the concentrated dosage used in therapy
