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Nrf2 activators like sulforaphane have a potential role with dual antiviral and anti-inflammatory properties in the management of viral pneumonia, a serious complication in COVID-19 disease (Bousquet et al., 2020

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showed that topical glutathionecyclodextrin (GSH-CD) increased intracellular GSH in mononuclear and red blood cells, decreased malondialdehyde (MDA), and significantly upregulated immune cytokines including IL-2, IFN-, IL-12p70, and TNF-

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