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Based on these findings, we ultimately culminate a rational design of a liposomal apparatus integrating oridonin, maleimide, and TLR2 targeting peptide for GSH depletion and specific cancer cells delivery

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In human capsular bag model, brief exposure to TGF (for only a few days) produced persistent fibrotic changes that continued for weeks after ligand removal, reflecting both de novo TGF production by LECs and the ability of the capsule to adsorb and re-present TGF, thereby prolonging profibrotic signaling (323)