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Common Causes of Melasma: Hormonal fluctuations (pregnancy, birth control pills, hormonal therapy) Sun exposure (UV rays trigger melanin production) Genetic predisposition Inflammation and skin irritation Certain medications and cosmetics While various treatments like chemical peel , laser therapy, and topical creams are used to manage melasma, many patients experience recurrence, irritation, or incomplete fading of dark patches
ScienceDirect , Schizophrenia Bulletin , vol
Fariss MW, Chan CB, Patel M, Van Houten B, Orrenius S
LandiS.2000Mammalian class theta GST and differential susceptibility to carcinogens: a review.4633(October 2000),247283,0027-5107 70