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These changes directly cause plasma leakage, retinal swelling, and the buildup of hard exudates that can interfere with vision, even before proliferative signs appear ( 2.1.5 Neurovascular unit dysfunction Emerging evidence also points to the role of neurovascular unit dysfunction in early DR

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In addition, it has been shown that AUC g post awakening is more stable across different days than daytime cortisol levels, which indicates less measurement errors in AUC g 35

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