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Data from observational studies and subgroup analyses of RCTs show that GLP-1 RAs reduce HF outcomes and mortality in obese HF patients across the LVEF spectrum

The tablets must be swallowed whole and should not be cut, chewed, or crushed

These findings supported the inclusion of the TRIUMPH-3 cardiovascular outcomes trial in the Phase 3 program

For example, liraglutide is a once-daily, subcutaneously administered, GLP-1 receptor agonist (229232)

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