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In many cases, tapering slowly may help the body adjust better and reduce the shock of increased hunger

Perhaps this reveals that we have not yet fully accepted obesity for what it truly is: not a condition to be temporarily corrected, but a chronic disease to be managed over time

Both classes lower blood glucose, promote weight loss, and reduce cardiovascular risk, but SGLT2 inhibitors have stronger evidence for kidney and heart failure protection and are generally preferred in those conditions

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Still, gut microbiota profiles may be considered as biomarkers or therapeutic targets