For example, we have previously done this with a dual GLP-1/GCG receptor agonist
Zepbound may increase heart rate and is not recommended in patients with severe gastrointestinal disease such as severe gastroparesis
For semaglutide, however, the reductions in glucagon (both postprandial and fasting) are clear
Why B12 Matters: Vitamin B12 is essential for: Red blood cell production DNA synthesis Nerve function Mental clarity Energy metabolism Its especially critical for vegetarians, vegans, older adults, or those with conditions like pernicious anemia or digestive malabsorption issues (e.g., celiac, Crohns, or low stomach acid)
~ Studies show it can be used to heal tendon injuries, tissue injuries, and eye injuries
The Bottom Line The main message of Weight maintenance after discontinuation of GLP-1 therapies is that stopping GLP-1 treatment often leads to weight regain and possible reversal of metabolic improvements