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Based on Phase 2 trial data, nausea associated with retatrutide is most common during the early weeks of treatment or following each dose increase, and typically diminishes over time as the body adjusts to the medication

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Therefore, normal tissue cells with high proliferative capacity are more likely to be subject to radiation injury (95)

Tirzepatide may cause gastrointestinal adverse effects that could lead to dehydration, potentially compounding hypotension risk, particularly in patients taking diuretics or renin-angiotensin system blockers

95% CI: 57.075.1%) were female