Young JZ, Isiegas C, Abel T, Nguyen PV (2006)
Additionally, CAFs are capable of breaking down the ECM through the release of matrix metalloproteinases (MMPs) and the creation of novel matrix proteins involved in tumor penetration and angiogenesis [51,52,53]
This causes the bursa to swell up like a rubber balloon filled with water
Johansen V, Gradel A, Holm SK, Cuenco J, Merrild C, Petersen N, et al
Early treatment is essential as delayed therapy can result in incomplete recovery or permanent damage
Higher concentrations reduce injection volume but may increase injection site discomfort balance convenience against subject comfort based on your protocol duration and frequency.