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Research shows that patients who stop semaglutide often regain a portion of lost weight within months, as appetite hormones return to baseline levels and eating patterns may revert

Participants who received the highest dose of orforglipron, 36 milligrams, lost 11.2% of their body weight - about 25 pounds on average - over more than 16 months

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We will also discuss the broader context of hormonal regulation and diabetes management to provide a comprehensive perspective on this topic

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