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A recent study looked at 13 research papers with 4275 patients

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Klucken J, Bchler C, Ors E, Kaminski WE, Porsch-Ozcrmez M, Liebisch G, Kapinsky M, Diederich W, Drobnik W, Dean M, Allikmets R, Schmitz G (2000) ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport

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Dietary supplements are not approved by the FDA before marketing in the same way as prescription drugs