Insulin exerts a synergistic effect with gonadotropins on both granulosa and theca cells: hyperinsulinemia amplifies luteinizing hormone (LH) signaling and upregulates the expression of steroidogenic enzymes, thereby promoting ovarian and adrenal androgen synthesis
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If your results show a mild deficiency and your GP confirms you dont have absorption issues, you can then try a high-dose sublingual spray for 3 months and re-test
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Reported side effects include water retention, flushing, headache, tingling in the extremities, elevated IGF-1 levels, impaired glucose tolerance, and injection site reactions including pain and infection risk