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Outcome measures include neurological severity scoring, rotarod and beam walk performance, histological assessment of lesion volume, and immunohistochemistry for axonal markers and myelin basic protein
Individual variation: Individual responses to L-carnitine supplementation can vary based on diet, genetics, and health status
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Future trials are essential to confirm these renal benefits and their applicability across diverse patient populations
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Of note, neuroinflammation has furthermore been implicated in the pathophysiology of depression [87], whereas increased inflammatory markers, such as C-reactive protein (CRP) or interleukin-2 (IL-2), have been specifically described to be more associated with the atypical subtype of depression [69]
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