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The result is oxidative stress (OS) which is linked to numerous disease processes including cognitive decline (Alzheimers disease) and other age-related conditions like cancer, cardiovascular disease, and diabetes
While GLP-1 medications were originally developed to treat diabetes, the drugs have exploded for their weight-loss potential
ArGLP-1 also reduced total mortality (HR 0.88, 95% CI 0.820.94, p = 0.0001) and hospital admission due to heart failure (HR 0.89, 95% CI 0.820.98, p = 0.013), all without increasing the risk of severe hypoglycemia, pancreatic problems or retinopathy.87 A recent post hoc analysis of CVOT with semaglutide has shown a gain in time free of cardiovascular disease of 1.7 years in those patients with CKD vs
No patients had unimproved NIRS data or NH 3 levels (Fig
Fun fact Glutathione levels naturally decline by up to 10% per decade after age 20
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