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For antimicrobial protection, avoid rubber closures, which can allow contamination through the hole where the needle passes, and may contain rubber additives
Endpoints: wound closure rate (planimetry, ImageJ), granulation tissue (histological scoring), collagen organization (Picrosirius red), re-epithelialization (H&E), tensile strength (mechanical testing)
TB-500 is a synthetic peptide modeled after thymosin beta-4, tested for its own role in tissue repair and inflammation
The waiver argument Hanes spent a long block on the podcast on what he sees as the procedural problem with the case
Regular injections may be needed initially, followed by maintenance doses
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