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Binding specificity and signal transduction of receptors for glucagon-like peptide-1(736)Amide and gastric inhibitory polypeptide on RINm5F insulinoma cells

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In terms of sitagliptin's binding mode, its trifluorophenyl motif binds with the hydrophobic S 1 pocket, forming -bonds with the essential Tyr547 residue (88)