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Primary Handling editor: Michael Basson, in collaboration with the Nature Medicine team

Alexis Pedrick: Sometimes they were given in ways that we recognize today, like in tablet form, but sometimes they were blended down into a pink liquid or given whole with anchovy paste to mask the taste, which really points to peoples desperation for weight loss

Yet millions of people around the world face environments that make it easier to gain weight and harder to stay healthy. Image Credits: David Trinks, KFF

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