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Looking ahead, the horizon for GLP-1 and related drugs is bright

2017;115(6):e40411

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Although the exact mechanism of how varicoceles affect sperm quality is not known, it is believed that this is usually through an increased heat effect

4,5 To date, the only approved acute pharmacological treatment is thrombolysis with tPA (tissue-type plasminogen activator), aimed at dissolving the thromboembolism and preserving the impaired, yet salvageable ischemic penumbra