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Early embryonic lethality caused by targeted disruption of the mouse PHGPx gene

Therefore, ADCs with non-cleavable linkers are even more dependent upon the biology of the target cells than cleavable linkers

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Here, to explore the regulatory role of TH in glucose metabolism, we compared hypothyroid mice to 3,5,3-triiodo-L-thyronine (T3)-treated hypothyroid mice with serum T3 concentrations close to those of euthyroid mice

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The method's consistency across different days and within the same day further validated its reliability