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The GTP-bound alpha subunit can move away and activate downstream pathways, and the beta and gamma subunits can also dissociate and trigger complementary pathways

It is essential to continue with prescribed treatments and lifestyle modifications whilst viewing any supplementation as potentially complementary rather than alternative to proven interventions

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Moreover, GIP administration reduces lipolysis-related genes expression in adipose tissue of overweight subjects and consequently decreases circulating free fatty acid levels [37]