What GHK-Cu adds to the formulation: Gene expression modulation across hundreds of genes including collagen genes (Type I, III), tissue inhibitors of metalloproteinases, anti-inflammatory mediators Collagen synthesis stimulation, specifically Type I and Type III collagen the structural proteins of skin, connective tissue, and many other tissues Anti-inflammatory signaling through investigated effects on TNF-, IL-6, and NF-B pathways Copper-peptide chemistry effects including cofactor activity for skin-relevant enzymes Skin-research and hair-research applications (the GHK-Cu literature in these areas is substantial) For the GHK-Cu deep-dive, see Copper Peptides Explained
At any of our five locations in Fayetteville, McDonough, Alpharetta, Buckhead, and Newnan, GA, Truffles Aesthetics offers B-12 injections for a rapid and powerful energy boost
Other agents are vitamin K, probenecid, naphthalene, nalidixic acid, dimercaprol, and phenylhydrazine
Safety & Precautions Generally well-tolerated
Always consult a healthcare professional before starting a new regimen
Neelakantan and colleagues (Biochem Pharmacol, 2017) then took the pharmacological step, reporting that selective, membrane-permeable small-molecule NNMT inhibitors reversed high-fat-diet-induced obesity in mice this is the study most directly relevant to the 5-Amino-1MQ class, because it moves from the target matters to a drug against the target does something in a live animal. And again, it is a mouse study