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After OGD treatment, the number of Ki-67-positive endothelial cells significantly decreased, while the intracellular expression levels of senescence markers P21, P53, and the DNA damage indicator -H2AX were markedly elevated (Figure 3B)

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Statistical analysis and data graphing were performed using IBM SPSS 26.0, GraphPad Prism 8.0.1, and R 4.3.2

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