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Zepbound and Mounjaro brief dosing guides Tirzepatide is available in the United States under two brand names, both manufactured by Eli Lilly: Mounjaro FDA-approved to improve blood sugar control in adults with type 2 diabetes, used alongside diet and exercise Zepbound FDA-approved for chronic weight management in adults with obesity, or adults who are overweight with at least one weight-related condition

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Among 21,822 people of European ancestry, we required participants to have complete data needed to construct the target phenotype and GWAS covariates (that is, data available for pre-treatment weight, post-treatment weight, drug type, dosage, time on treatment and factors such as age, sex and height), resulting in 18,488 participants